Frailty is relevant to cardiology because the disease process predispose to physical impairments that ultimate worsen the cardiovascular illness.

The phenomenon of increased vulnerability to stressors due to decreased physiological reserves leads to poor clinical outcomes after cardiovascular insults. Equally CVD worsens frailty due to hospitalisation, debilitation, immobility, systemic illness that underpins physiological deterioration in physical frailty. In cardiology, frailty is highly prevalent in patients with heart failure, valvular heart disease, but also myocardial infarction.